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Doktor

PD Dr. rer. nat. Gudrun Ulrich-Merzenich

Head of the Work Group „Synergy Research and Experimental Medicine“

Academic Education und Qualifications

1984 – 1990 Studies of Biology, Pharmacology and Botany at the Faculty of Biology of Ruhr-University of
Bochum / Germany. University Diploma (= MSc) in Biology at the Institute of Pharmcology and Toxicology, Medical Faculty of the Ruhr-University of Bochum / Germany
Thesis: Compartimentation of the enteral oxydative dealkylation and sulfoconjugation: comparative studies with p-nitroanisol and p-nitrophenol
1990 – 1992 Scholarship of the German Academic Exchange Service (DAAD) and the Indian Council for Cultural Relations (ICCR) for studies and research in Ayurvedic Medicine at the Banares Hindu University, Varanasi / India, the Gujarat Ayurvedic University, Jamnagar / India and the Bharati Vidyapeeth College of Ayurveda, Pune / India
1992 – 1997 Research Fellow (ICCR) at the National Centre for Cell Science, Pune / India, at the Bharati Vidyapeeth College of Ayurveda (Pune University), the Sane Guruji Hospital and the Set Tarachand Hospital, Pune / India and PhD-student at the Medical Policlinic, Faculty of Medicine, University of Bonn / Germany including research periods at the Children’s Hospital, Harvard Medical School, Boston / USA
1998 PhD (Dr. rer.nat.) in Natural Sciences at the Rheinische Friedrich-Wilhelms-University of
Bonn / Germany. Main subjects: Biochemistry / Pharmacology and Genetics.
Topic of the PhD Thesis: Hyaluronic Acid and other Glycosaminoglycans in Rheumatoid Arthritis. Biochemical and Clinical Aspects
2008 Habilitation and venia legendi for ”Experimental Medicine“ at the Medical Faculty of the
Rheinische Friedrich-Wilhelms-University of Bonn / Germany
Topic of the Habilitation Thesis: Atheroprotective Effects of Antioxidants

Positions and Assignments

1981 – 1983 Service in the United Nations Development Programme (UNDP) as United Nations Volunteer in Sri Lanka www.podiespice.com
Link zu Artikel: Dort wo der Pfeffer wächst (Walter Keller, Südasien, als PDF)
since 1999 Senior Scientist, Medical Policlinic, Rheinische Friedrich-Wilhelms-University, Bonn, Germany
2001 – 2005 Head of the Scientific Laboratories of the Medical Policlinic of the Rheinische Friedrich-Wilhelms-University of Bonn, Germany
2009 – 2013 Co-Editor of the Scientific Journal „Phytomedicine“
Link zu Phytomedicine Journal: www.journals.elsevier.com/phytomedicine
Since 2013 Initiator and Editor-in-Chief of the Scientific Journal „Synergy“
Link zu Synergy Journal: www.journals.elsevier.com/synergy
Since 2013 Head of the work group on Synergy Research at the Medical Clinic III, UKB, Bonn
Link zu Forschungsgruppe: AG Ulrich-Merzenich

Memberships in Professional Associations:

  • Society for Medicinal Plant and Natural Product Research (GA)
  • German Society for Hematology and Medical Oncology (DGHO)
  • Forum of University Work Groups for Naturopathy and Complementary Medicine
  • Society for Phytotherapy e.v. (GPT), member of scientific advisory board (2010-2013), member of board of directors (2013-2016)
  • Regional Cooperative Centre for Rheumatology Aachen-Köln-Bonn
  • German Association of University Professors and Lecturers

Reviewer for Scientific Journals:

  • Circulation
  • Cell Biology and Toxicology
  • European Journal of Nutrition
  • International Journal of Trace Elements in Medicine and Biology
  • Planta Medica
  • Journal of Ethnopharmakology
  • PlosOne
  • Molecular Nutrition
  • Rheumatology International
  • Swiss Journal for Integrative Medicine
  • Stem Cell Research
  • Wiener Medizinische Wochenschrift

List of Publications

Original Articles

1. Totzke G, Metzner C, Ulrich-Merzenich G, Ko Y, Sachinidis A, Vetter H. Effect of vitamin E and C on the DNA synthesis of human umbilical arterial endothelial cells. Eur J Nutr 2001;40(3):121-6.

2. Ulrich-Merzenich G, Metzner C, Schiermeyer B, Vetter H. Vitamin C and vitamin E antagonistically modulate human vascular endothelial and smooth muscle cell DNA synthesis and proliferation. Eur J Nutr 2002; 41(1): 27-34.

3. Ulrich-Merzenich G, Metzner C, Bhonde RR, Malsch G, Schiermeyer B, Vetter H.
Simultaneous isolation of endothelial and smooth muscle cells from human umbilical artery or vein and their growth response to low density lipoproteins. In vitro Cell Dev Biol Anim 2002; 38(5):265-72.

4. Lottermoser K, Ulrich-Merzenich G, Vetter H, Düsing R. Wirkung von Angiotensin II auf Entzündungsmediatoren bei gesunden Probanden. Dtsch Med Wochenschr 2003; 128:2470-5.

5. Zeitler H*, Ulrich-Merzenich G*, Hess l, Konsek E, Unkrig C, Walger P, Vetter H, Brackmann HH. Treatment of acquired hemophilia by the Bonn-Malmo Protocoll: documentation of an in vivo modulating concept. Blood 2005;15:105(6):2287-93.

6. Zeitler H*, Ulrich-Merzenich G*, Hoffmann L, Kornblum C, Schmidt S, Vetter H, Walger P. Long-term effects of a multimodal approach including immunoadsorption for the treatment of myasthenic crisis. Artif Organs. 2006, 30(8):597-605.

7. Zeitler H*, Ulrich-Merzenich G*, Walger P, Düsing R, Vetter H. Das modifizierte Bonn-Malmö-Protokoll (MBMP) in der Behandlung der erworbenen Hemmkörperhämophilie. Dtsch Med Wochenschr 2006:131(4):141-7.

8. Zeitler H*, Ulrich-Merzenich G*, Walger P, Vetter H, Oldenburg J, Goldmann G, Brackmann HH. Treatment of Factor VIII Inhibitors with selective IgG Immunoadsorption- a single centre experience in 50 patients with acquired hemophilia. Transfus Medicine and Hemotherapy 2006;33:160-164

9. Ulrich-Merzenich G, Zeitler H, Panek D, Bokemeyer D, Vetter H. Vitamin C promotes human endothelial cell growth via ERK-signaling pathway. Eur J Nutr 2007;46:87-94.

10. Ulrich-Merzenich G, Zeitler H, Vetter H, Bhonde RR. Protective effects of taurine on endothelial cells impaired by high glucose and oxidized low density lipoproteins. Eur J Nut 2007; 46 (8):431-8.

11. Zeitler H*, Ulrich-Merzenich G*, Walger P, Bartels M, Goldmann G, Vetter H, Oldenburg J. Treatment of Adults with clinically suspected severe Thrombotic Thrombocytopenic Purpura- Experience of a single Centre. Transfusion Medicine and Hemotherapie 2007;34:64:72.

12. Seidel M, Fiebich BL, Ulrich-Merzenich G, Candelario-Jalil E, Koch FW, Vetter H. Seretonin mediates PGE2 overexpression through 5-HT2A and 5-HT3 receptor subtypes in serum-free tissue culture of macrophage like synovial cells.
Rheumatol Int 2008(10):1354-6.

13. Zeitler H, Ulrich-Merzenich G, Panek D, Goldmann G, Vidovic N, Oldenburg J. Immunoadsorption in the treatment of acquired haemophilia. Atheroscler Suppl 2009; 10:122-5.

14. Zeitler H, Ulrich-Merzenich G, Goldmann G, Vidovic N, Brackmann HH, Oldenburg J. The relevance of the bleeding severity in the treatment of acquired haemophilia – an update of a single centre experience with 67 patients.
Haemophilia 2010,16(102)1354-6.

15. Müller N, Ellinger S, Alteheld B, Ulrich-Merzenich G, Berthold H, Vetter H, Stehle P. Bolus ingestions of white and green tea stabilizes plasma antioxidant capacity, but does not affect markers of oxidative stress in healthy adults.
Mol Nutr Food Res. 2010; 54(11):1636-19.

16. Ulrich-Merzenich G, Koptina A, Kelber O, Freischmidt A, Heilmann J, Müller J, Sadeghlar F, Zeitler H, Wagner H. Gene expression profiles obtained in vivo for the prediction of adverse events exemplified for salicylate containing phytopharmaceuticals and the tricyclic antidepressant Imipramine. Phytomedicine 2012,19(3-4):322-9.Epub 2011Nov25

17. Ulrich-Merzenich G, Kelber O, Koptina A, Freischmidt A, Heilmann J, Müller J, Zeitler H, Seidel MF, Ludwig M, Heinrich EU, Winterhoff H† Standardized willow bark preparation shows antidepressant like effects. Phytomedicine 2012;19(10):930-9.Epub 2012 Jun 27.

18. Zeitler H, Ulrich-Merzenich G, Panek D , Goldmann G, Vidovic N, Brackmann HH , Oldenburg J. The Benefit of Extracorporeal Treatment for the acute und Long-Term Outcome of Patients with Life Threatening Acquired Haemophilia.
Transfusion Medicine and Hemotherapie 2012;39(4):264-270. Epub 2012 Jul 26

19. Flower A, Witt C, Liu JP, Ulrich-Merzenich G, Muir K, Yu H, Prude M, Lewith G. GP-TCM Guidelines for randomized controlled trials investigating Chinese herbal medicine (CHM). (Excecutive Summary) J Ethnopharmacol 2012, 140(3):550-4.

20. Zeitler H, Goldmann G, Marquardt N, Ulrich-Merzenich G. Long term outcome of patients with acquired haemophilia. A monocentre interim analysis of 82 patients. Atherosclerosis Suppl 2013;14:223-228

21. Zeitler H, Ulrich-Merzenich G, Goldmann G, Marquardt N, Oldenburg J. Immunoadsorption as successful Treatment for pregnancy-associated severe Acquired Haemophilia. Therapeutic Apharesis and Dialysis 2014, 18(1): 103-110.

22. Flower A, Witt C, Liu JP, Ulrich-Merzenich G, Muir K, Yu H, Prude M, Lewith G. GP-TCM Guidelines for randomized controlled trials investigating Chinese herbal medicine (CHM). (Full version) Eur J Integr Med 2014;6,(2):186-210

23. Orland A, Knapp K, König GM, Ulrich-Merzenich G, Knöss W. Combining Metabolomic Analysis and Microarray Gene Expression Analysis in the Characterization of the Medicinal Plant Chelidonii majus L. Phytomedicine 2014 [accepted]

24. Zacharski DM, Brandt S, Esch S, König S, Mormann M, Ulrich-Merzenich G, Hensel A. Xyloglucan from Tropaeolum majus Seeds Induces Cellular Differentiation of Human Keratinocytes by Inhibition of EGFR Phosphorylation and Decreased Activity of Transcription Factor CREB. Biomacromolecules. 2015 Jul 13;16(7):2157-67.

25. Abdel-Aziz H, Schneider M, Neuhuber W, Kassem AM, Khailah S, Müller J, Eldeen HG, Khairy A, Khayyal MT, Shcherbakova A, Efferth T, Ulrich-Merzenich G. GPR84 and TREM-1 signaling contribute to the pathogenesis of reflux esophagitis. Mol Med 2015; 21:1011-1024.
*both authors have contributed equally to the work


Reviews

26. Metzner C, Ulrich-Merzenich G, Lüder W. Arginin und Taurin- präventive Nahrungsfaktoren bei kardiovaskulären Erkrankungen? Ernährungs-Umschau 2001;48:188-192.

27. Ulrich-Merzenich G, Zeitler H, Jobst D, Panek D, Vetter H. Application of the „Omic“-technologies in phytomedicine.
Phytomedicine. 2007;14(1):70-82. Reprint with permission: Journal for Natural Remedies 2007; 7:1-18
Revista de Fitoterapia 2007;7(2):115-129 (Applicación de las tecnologias ómicas a la Fitoterapia , in spanischer Sprache)

28. Ulrich-Merzenich G, Zeitler H, Vetter H, Kraft K. Synergy research: vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signaling. Phytomedicine 2009;16(1):2-16.

29. Wagner H, Ulrich-Merzenich G. Synergy research: Approaching a new generation of phytopharmaceuticals.
Phytomedicine 2009, 16(2-3): 97-110. Reprint with permission: Journal for Natural Remedies 2009, 9(2):121-141.)

30. Ulrich-Merzenich G, Zeitler H, Panek D, Wagner H, Vetter H. New perspectives for synergy research with the „omic“-technologies. Phytomedicine 2009;16(6-7):495-508

31. Ulrich-Merzenich G, Panek D, Zeitler H,Vetter H, Wagner H. Drug Development from Natural Products exploiting Synergy effects. Ind J Exp Biol 2010, 48(3): 208-19.

32. Ellinger S, Müller N, Stehle P, Ulrich-Merzenich G. Consumption of green tea or green tea products: Is there an evidence for antioxidant effects from controlled interventional studies? Phytomedicine 2011, 18 (11): 903-5.

33. Ulrich-Merzenich G, Zeitler H. The lectin like oxidized LDL-receptor 1 in atherosclerosis, inflammation and longevity. Exp Opin Ther Targ 2013;17(8):905-19.

Short Communications /Letter to the Editor

34. Ulrich-Merzenich G, Bhonde RR. Donor site, age, and health affect fibroblast growth in culture. In Vitro Cell Dev Biol Anim 1995 (7): 494-6.

35. Ulrich-Merzenich G, Kraft K, Singh LM. Rheumatic diseases in Ayurveda: a historical perspective. Arthritis Rheum 1999; 42(7):15553-5. ]

36. Seidel MF, Ulrich-Merzenich G, Vetter H, Düsing R. Normal concentrations of serum hyaluronic acid in patients with fibromyalgia syndrome. Clin Exp Rheumatol 2006; 22(1): 137.


Case Reports

37. Zeitler H*, Ulrich-Merzenich G*, Richter J. Multiple symetric lipomas- differential diagnosis to obesity, a treatment option for fibrates? Obesity surgery 2008 (10):1354-6.


Supplements

38. Seidel MF, Ulrich-Merzenich G, Fiebich B, Candelario-Jalli E, Koch FW, Vetter H. Tropisetron inhibits serontonin-induced PGE2 release from macrophage-like synovial cells in serum-free tissue culture medium. Scand J Rheumatol Suppl 2004;119:33


Guidelines / Consensus Papers

39. Co-author of the “Guidelines for randomized controlled trials investigating Chinese herbal medicine (CHM)” (WP6: Pharmacology in Clinical Studies) in the Framework of the European Action Coordination Programmes (FP7) “Good Practice in Traditional Chinese Medicine Research in the post-genomic area” (www.gp-tcm.or)

40. Participant and Contributor: Consensus paper on Tibetan medicine Expert conference on Tibetan Medicine, March 2010, University Center of Medicine Charité, Berlin, Germany, Organized by Prof. Dr. C. Witt. Estimated date of publication: 2012


Publications in non-JCR-Journals

41. Jobst D, Ulrich-Merzenich G, Dem Schmerz multimodal zu Leibe rücken. Der Hausarzt 2005;13:45-48.

42. Metzner C, Ulrich-Merzenich G, Ernährungstherapie des metabolischen Syndroms und des Diabetes mellitus mit Naturstoffen (Ballaststoffe, Fettsäuren). Vitaminspur 2001;16:123-126, Hippokrates Verlag

43. Ulrich-Merzenich G, Sucher N. Editorial. Synergy 2014;1(1):1-2

44. Ulrich-Merzenich GS. Combination screening of synthetic drugs and plant derived natural products—Potential and challenges for drug development. Synergy 2014; 1(1): 2014: 59-69.

45. Orland A, Knapp K, König GM, Knöss W, Ulrich-Merzenich G. Differential transcriptional profiles in HepG2 cells after the exposure to a chemically characterized complex preparation of Silybi mariani fructus and its chemically defined constituent silybin A + B. Synergy 2014; 1 (2):99-108.

46. Liu JP, Chen, KJ, Fei YT, Gao R, Chen W, Cao HJ, Zhang Y, Liu ZL, Li X, Han M, Wang LQ, Wang M, Yang GY , Yu H, Xia Y, Chen NN, Feng S, Sun J, Flower A, Witt C, Lewith G, Ulrich-Merzenich G, Muire K, Prude M. Methodology guideline for clinical studies investigating traditional Chinese medicine and integrative medicine. Complementary Therapies in Medicine 2015; 23(5):751-756.

47. Fu J, Zhang N, Chou JH, Dong HJ, Lin SF, Ulrich-Merzenich G, Chou TC. Drug combination in vivo using combination index method: Taxotere and T607 against colon carcinoma HCT-116 xenograft tumor in nude mice. Synergy 2016; 3 (3): 15-30.


Books

48. Evidence and rational based research on Chinese Drugs, Springer Publishing House 2013;
Editors: H. Wagner, G. Ulrich-Merzenich
Wagner, H., Ulrich-Merzenich, G. Editorial
Wagner H, Ulrich-Merzenich G. Towards a contemporary and evidence-based development of TCM. Book chapter: 489-517.


Presentations at scientific conferences (printed abstracts)

49. Lauterbach F, Ulrich-Merzenich G, Rühl H . Kompartimentierung der enteralen Desalkylierung und Sulfokonjugation: vergleichende Untersuchungen mit p-Nitroanisol und p-Nitrophenol. Naunym-Schmiedeberg’s Arch Pharmacol 1990. 343:R10.

50. Ulrich-Merzenich G, Seidel MF, Varga B, Stratz T, Vetter H, Müller W. Hyaluronsäurekonzentrationen im Serum von Patienten mit Fibromyalgiesyndrom sind nur in einer Untergruppe erheblich erhöht. Kongress der Deutschen Gesellschaft für Rheumatologie, Aachen, Z Rheumatol 2000;59(3):III/59.

51. Ulrich-Merzenich G, Mojamdar M, Kraft K, Vetter H. The hyaluronan production is increased in skin fibroblasts of patients with rheumatoid arthritis. Kongress der Deutschen Gesellschaft für Rheumatologie, Leipzig. Z Rheumatol 2001;60(1):I/104.

52. Seidel MF, Ulrich-Merzenich G, Spehler R, Vetter H. Polymorphe Arthrose-Synovialzelle koexprimieren Marker für Fibroblasten und CD68 unter serumfreien Zellkulturbedingungen. Kongress der Deutschen Gesellschaft für Rheumatologie, Leipzig. Z Rheumato 2001;60(1): I/63.

53. Ulrich-Merzenich G, Joshi YG, Desai A, Hatankar V, Deshpande M, Mardikar R, Singh LM, Kraft K. Documentation of the management of rheumatoid arthritis by traditional herbal drug preparations in India. Fact 5(1):22.

54. Seidel MF, Ulrich-Merzenich G, Fiebich B, Candelario-Jalil E, Koch FW, Vetter H. Serotonin is a potent inflammatory mediator for macrophage like synovial cells in serum-free tissue culture. EULAR-Konferenz Berlin; Ann Rheum Dis 2004;63(Supp1):527.

55. Lottermoser, Ulrich-Merzenich G, Vetter H, Düsing R. Effect of angiotensin II on mediators of inflammation in healthy volunteers. Dtsch Med Wochenschr 2003;128:S184 Supplement 3.

56. Ulrich-Merzenich G, Hausen A, Desai A, Schiermeyer B, Ludwig M, Vetter H. Influence of the variant mannose-binding lectin genotypes and the TNF-alpha promotorpolymorphism (-308 G/A) on rheumatoid arthritis. Kongress der Deutschen Gesellschaft für Rheumatologie, Frankfurt. Z Rheumatol 2003;62:1/72.

57. Müller N. Schlüter V., Scharfhausen J, Ellinger S, Alteheld B, Ulrich-Merzenich G, Vetter H, Berthold HK, Stehle P. Bolustage von weißem oder grünem Tee stabilisiert das extrazelluläre pro/antioxidative Gleichgewicht, schützt jedoch nicht vor H2O2-induzierten DNA-Strangbrüchen in Leukozyten. Proc Germ Nutr. Soc 2007(10):VIII-8.

58. Ulrich-Merzenich G, Jobst D, Zeitler H, Müller J, Vetter H. Synergistic effects of phytopreparations. Planta medica 2007;73:812. 55th International Congress and Annual Meeting of the Society for Medicinal Plant Research, September 2-6; 2007; Graz, Austria.

59. Ulrich-Merzenich G, Jobst D, Hartbrod F, Zeitler H, Müller J, Vetter H. Gen- und Proteinexpressionsanalysen zur Standardisierung und Wirksamkeitsanalyse von Phytotherapeutika am Beispiel von salicinhaltigen Rindenextrakten. Zeitschrift für Phytotherapie 2008;29 (Supp. 1); S17.

60. Ulrich-Merzenich G, Hartbrod F, Jobst D, Zeitler H, Vetter H.
Comparison of gene- and proteinexpression profiles of a standardized willow bark extract
with quercetin and nonsteroidal antiinflammatory drugs in human chondrocytes. 56th
International Congress and Annual Meeting of the Society for Medicinal Plant Research,
Planta Medica 2008, 74: 916. SL41

61. Ulrich-Merzenich G, Hartbrod F, Jobst D, Zeitler H, Vetter H.
Vergleich der Gen- und Protein- Expressionsprofile eines standardisierten
Weidenrindenextraktes mit Quercetin und nicht steroidalen Antirheumatika in humanen
Chondrozyten. Kongress der DGRH/ARO, Berlin 2008, ER3.02

62. Ulrich-Merzenich G, Hartbrod F, Jobst D, Zeitler H, Müller J, Vetter H.
Immunomodulation by the multiextract mixture Phytodolor in fibroblasts
Kongress der DGRH/ARO, Berlin 2008;ER.04.

63. Ulrich-Merzenich G, Panek D, Zeitler H, Heilmann J, Freischmitt A, Kelber O, Müller J, Winterhoff H. Gene expression profiling of blood cells from rats treated with different fractions of a standarized aequous willow bark extract – evidence for immuno- and neuromodulatory activities. 57th International Congress and Annual Meeting of the Society for Medicinal Plant Research, Planta medica 2009; 75. 898 SL53. (oral presentation)

64. Ulrich-Merzenich G, Panek D, Zeitler H, Heilmann J, Freischmidt A, Kelber O, Müller J; Winterhoff H. Neueste Ergebnisse aus der Weidenrindenforschung mittels „Omic“ – Technologien. Z Phytotherapie 2009; 30 (Suppl. 1) S16.

65. Ulrich-Merzenich G, Zeitler H, Panek D, Kraft K. Neubewertung von Antioxidantien bei kardiovaskulären Erkrankungen. Z Phytotherapie 2009; 30 (Suppl. 1) S17.

66. Ulrich-Merzenich G, Zeitler H, Hausen A, Joshi YG, Desai A, Vetter H, Kraft K. The benefit of ayurvedic diagnostics in treatment strategies for rheumatoid arthritis.
Eur J Integ Med 2009, 1(4): 198

67. Ulrich-Merzenich G, Kelber O, Freischmidt A, Heilmann J, Müller J, Zeitler H, Panek D, Winterhoff H. Evidences for an antidepressant effect of willow bark in the Porsolt swimming test, (Dezember 2010) 3rd Europ. Congress for Integr. Medicine. Euro J Integ Med

68. Ulrich-Merzenich G, Koptina A, Kelber O, Freischmidt A, Heilmann J, Müller J, Zeitler H, Panek D, Winterhoff H† Comparative analysis of gene expression profiles from rats treated with a standardized willow bark preparation, its salicin rich ethanol fraction and imipramine for toxicological endpoints. 59th International Congress and Annual Meeting of the Society for Medicinal Plant Research, Planta medica 2011, GA-September 2011

69. Kelber, O., Okpanyi, S.N., Freischmidt A, Heinrich EU, Müller J, Heilmann J, Ulrich-Merzenich, G., Weiser, D. Antidepressant mechanisms of action of willow bark extract STW 33-I. Planta medica 2011, GA September 2011, (Poster).

70. Ulrich-Merzenich G., Koptina A, Kelber O, Müller J, Sadeghlar F, Wagner H. Inflammation in neurodegenerative diseases. Eur J of Integ Med 2011, 4th European Congress of Integrative Medicine (ECIM) November 2011, Berlin.

71. Koptina A, Shcherbakova A, Shvetsov S, Soldati F, Romanov EM, Ulrich-Merzenich G. Chemical composition of Cladonia sylvatica (L.) Hoffm. 60th International Congress and Annual Meeting of the Society for Medicinal Plant Research, Planta medica 2012, GA-July 2012.

72. Koptina A, Kelber O, Zeitler H , Abdel-Aziz H, Ludwig M, Wagner H, Ulrich-Merzenich G.
Targeting of the LOX-1 receptor by willow bark, its EtOH-Fraction and by the antidepressant imipramine. . 60th International Congress and Annual Meeting of the Society for Medicinal Plant Research, Planta medica 2012, GA-July New York, 2012.

73. Ulrich-Merzenich G, Desai A, Pendse , Kakunkar V, Deshpande M , Hatankar V, Zeitler H, Hausen A, Vetter H, Kraft K, Joshi YG. Integrating Concepts and Herbs of Ayurvedic Medicine into the Treatment of Rheumatoid Arthritis. Society of Ethnopharmacol. Graz, September 2012.

74. Ulrich-Merzenich G, Kelber O, Weiser D, Khayyal MT, Abdel-Aziz H. A multitarget approach by STW5: the inhibition of a proinflammatory signature, the increase of membrane-bound mucins and the restoration of barrier function improves esophagitis in rats GA, Münster 2013, Planta medica 2013

75. Ammar RM, Ulrich-Merzenich G, El-Azab MF, Moustafa YM. Antitumor Potential of the Endocannabinoid Reuptake Inhibitor OMDM-2. Annual meeting of the German, Austrian and Swiss Associations for Hematology and Oncology (DGHO)m 18tg-22th October, Vienna, Austria 2013.

76. Ammar RM, Ulrich-Merzenich G, El-Azab MF, Moustafa YM. Inhibition of the endocannabinoid reuptake is an innovative strategy to imped tumor growth and angiogenesis. 23rd Annual Symposium on the Cannabinoids, 21-26th June, ICRS 2013; Vancouver, Cannada .

77. Ammar RA, Ulrich-Merzenich G. Curcumin synergizes with the endocannabinoid reuptake inhibitor OMDM-2 to inhibit the proliferation of the human glioblastoma cell line U-87 Phytopharm 2014, St. Petersburg

78. Ulrich-Merzenich G, Kelber O, Khayyal MT, Abdel-Aziz H. Multitargeting by STW5 in a rat model for gastroesophageal reflux disease and in HET1A-cells involves MAP-Kinase and G-protein coupled receptor signalling. Planta medica 2014

79. Abdel-Aziz H, Kelber O, Khayyal MT, Ulrich-Merzenich G. Receptor modulation and MAP-kinase signaling induced by STW5 and by the proton-pump inhibitor omeprazole in a rat model for gastroesophageal reflux disease and in HET1A cells. UEG Week 2014 – UEG14ABS-5267. 80. Ulrich-Merzenich G. Combination Therapies and Synergy Effects . Phytopharm 2014.

81. Ulrich-Merzenich G, Panek D, Goldmann G, Oldenburg J, Zeitler H. FoxP3 + subpopulation dynamics during the immune tolerance induction in acquired haemophilia. Deutsche Gesellschaft für Immunologie 2014.

82. Ulrich-Merzenich G, Shcherbakova A, Kelber O, Abdel-Aziz H. Pain sensation in grastro-esophageal reflux disease may be mediated by acid sensing ion channels- evidence for novel targets of STW5 derived from a rat model. Planta Medica 2016;81(S01):S1-S381.

83. Ulrich-Merzenich G, Shcherbakova A, Kelber O, Abdel-Aziz H. Elimination of undesirable modes of actions by combining different plant extracts- the example of STW5. Planta medica 2016;81(S01):S1-S381.

84. Shcherbakova A, Nyugen L, Koptina A, Backlund A, Shurgin A, Romanov E, Ulrich-Merzenich G. Screening of compounds of Evernia prunastri (L.) for their antiproliferative activity in glioblastoma cells. Planta medica 2016;81(S01):S1-S381.

85. G Ulrich-Merzenich, LJ Jürgens, A Shcherbakova, A Tüschen, I Tuleta, UR Jürgens
Kontrolle der erhöhten ex vivo Th1/Th2-Aktivität bei Asthma durch Omalizumab in vitro, 58. Kongress der Deutschen Gesellschaft für Pneumonologie und Beatmungsmedizin. 22.-25. März 2017, Stuttgart.

86. Ulrich-Merzenich G. Combination-Therapies and Synergy-Effects, Phytopharm 2017; 2.-5. Juli 2017 Graz, AU


Popular Books (Co-Author) (German language)

87. Merzenich, B. Gewürze- Konsequenzen des Geschmacks
Edition Dia, St. Gallen 1984

88. Merzenich B, Imfeld A. Tee-Konsequenzen des Geschmacks
Edition Dia, St. Gallen/ Wuppertal 1986